Why this topic is important
Migraine affects approximately 15% of the global population, significantly
impacting quality of life and productivity. While advancements in
pharmacological treatments such as CGRP inhibitors have shown promise,
up to 66% of patients fail to respond to these therapies. Personalized
medicine, which tailors treatment based on individual patient profiles, is
crucial for improving outcomes.
This study by Di Antonio et al. (2023) uses cluster analysis to classify migraine
patients into distinct subgroups based on clinical and psychophysical
characteristics. By identifying variations in pain sensitivity, musculoskeletal
dysfunctions, and headache-related disability, these findings pave the way
for targeted therapies and enhanced care strategies.

NOTES

A Psychophysical profiling identifies meaningful subgroups among migraine patients, guiding targeted interventions.

A Subgroups with combined pain sensitivity and musculoskeletal dysfunction require multidisciplinary management strategies.

A Routine use of AROM and PPT tools in clinical settings enhances diagnostic precision and treatment customization.

A Ongoing research is needed to refine these findings and develop standardized protocols for personalized

care.